Fatty Bases For Suppositories Market Report
Fatty Bases for Suppositories Market, by Excipient Base Type [Hard fat, Macrogol (PEG), Glycerol+Water, Gelatin, Cocoa Butter], Regional Analysis (North America, Europe, Asia Pacific, LAMEA): Global Opportunity Analysis and Industry Forecast, 2020–2027
The global fatty bases for suppositories market forecast is predicted tobe $6,565.1 million by 2027, increasing from $5,246.5 million in 2019 at a healthy CAGR of 2.7%. Europe’s fatty bases for suppositories market is expected to grow at a healthy CAGR of 3.2% by generating a revenue of $1,981.3 million, during the projected period. Rise in the geriatric population is one of the major factors for the growth of the European market.
Fatty bases for suppositories Market Analysis:
Suppositories are solid or semi-solid dosages of multiple shapes and weights, adapted for introduction into the vaginal, rectal, or urethral ori?ce of the human body. The suppositories melt or dissolve at body temperature. This suppository acts as a protectant or as a therapeutic carrier for systemic action.
The huge significance of fat suppositories in the geriatric and pediatric patients is anticipated to drive the global market
The fat-based excipients play a significant role in drug delivery, mainly in pediatric and geriatric patients. The rectal route serves a great alternative for drug delivery amongst these populations. Also, the rising need for fat-based suppositories owing to their advantages such as rapid absorption of multiple low molecular weight drugs and the potential for absorption into the lymphatic system, is expected to boost the market growth, over the forecasted period.
Furthermore, the rising number of product launches are expected to create an enormous opportunity for the global market growth. For example, in July 2017, Cipla launched oil-based rectal suppositories to treat pediatric patients suffering from malaria. In addition, excellent physical and chemical stability, neutrality towards mucous membranes, and their extensive compatibility with almost all active compounds are also projected to drive the growth of the global fatty bases for suppositories market, during the analysis period.
To know more about Fatty bases for suppositories Market Drivers, get in touch with our analysts here.
The reluctance of patients to prefer rectal drug delivery is anticipated to restrain the global Fatty bases for suppositories market growth
Though having a long history of use for vaginal and rectal drug delivery, the current global market for fatty bases for suppositories is obstructed mainly due to a lack of user acceptability and willingness to use rectal products. Moreover, complexities associated with the manufacturing of oil-based suppositories are estimated to hamper the growth of the market to a certain extent.
The importance of fat excipients for the treatment of viral infections is expected to create a lucrative opportunity in the global market
The modern-day healthcare industries are seeking better substitutes and improved medication that could effectively help patients to recover from infectious disorders. Continuous ongoing research work across the world by multiple institutions, biotech, and pharmaceutical companies shows a significant chance of developing antiretroviral suppository drug delivery medication. Control of virus infection and disease strategies such as topical vaginal and rectal microbicides have shown positive effects and provide vital antiretroviral therapy. These delivery systems are being developed majorly and provide affordable and effective options for high-risk patients. Presently, multiple strategies are under development and being investigated for vaginal and rectal topical antiviral drug delivery systems. Due to such elements, the demand for fat-based suppositories will rise extensively across the world.
To know more about fatty bases for suppositories market opportunities, get in touch with our analysts here.
Fatty bases for suppositories Market, by Excipient Type:
Hard fat segment will have significant market share in the global market and is expected to generate a revenue of $3,039.1 million by 2027, mainly because of its dynamic properties
Source: Research Dive Analysis
Hard fat has the highest market share in 2020 and the segment is expected to register a revenue of $3,039.1 million by 2027, rising from $2,385.4 million in 2019; this is mainly owing to certain versatile properties of hard fat excipient base. Depending on molecular weight, hard fat excipients can be produced to exhibit a broad range of melting points, firmness, and dissolving rates. These factors are expected to boost the growth of hard fat in the analysis period.
Glycerol+water suppositories will have rapid growth and the segment is projected to generate a revenue of $173.1 million by 2027, surging from $120.3 million in 2019. Glycerol excipients are mild rectal laxatives that are mainly used to relieve constipation. Glycerol acts as a lubricant; thus, this suppository is highly effective, safe, and doesn’t react with other medications. These key factors are projected to propel the global market growth.
North America region shall have a significant market share, and it is anticipated to register a revenue of $2,410.2 million, over the analysis timeframe.
Source: Research Dive Analysis
The fatty bases for suppositories market size in North America registered a revenue of $1,988.5 million in 2019 and it is expected to account for $2,410.2 million by 2027; this is mainly due to the rising patients of gynecological diseases and urology disorders in the region. For example, as per a recently published report of CDC, in the US, bacterial vaginosis (BV) is one of the most common bacterial infections and approximately 30% of women of reproductive age suffer from such diseases. These factors may lead to foster the growth of the North America market, in the forecast period.
Europe region fatty bases for suppositories market share is anticipated to rise at a CAGR of 3.2% by generating a revenue of $1,981.3 million by 2027. High spendings in R&D departments, along with increasing technological advancements are expected to foster the demand for fatty bases for suppositories drugs, and it is further projected to increase the European fatty bases for suppositories market growth. In addition, countries such as Spain, Italy, and Germany, are witnessing huge growth in the geriatric population. For instance, as per the recent publication of the United Nations (UN), the global population will reach around 10 billion; whereas, in Europe, it will reduce by as much as 26 million by the end of 2050. This rising geriatric population is vulnerable to chronic diseases such as cardiovascular conditions, constipation, and diabetes. An increase in the prevalence of these health disorders is expected to propel the demand for medications, which will eventually drive the growth of the global fat-based suppositories in the European market.
Competitive Scenario in the Global Fatty bases for suppositories Market:
Mergers & acquisitions, along with advanced product development are the frequent strategies followed by the leading market players
Source: Research Dive Analysis
Some of the leading Fatty bases for suppositories key players include Unither, Bliss GVS Pharma Ltd., Delpharm, ATRAL, Aenova Holding GmBH, FAMAR, LGV (Laboratories Mayoly Spindler), Priyans Drugs. Fatty bases for suppositories industry players are concentrating on technological advancements, showcasing product portfolio, and mergers & acquisitions.
Porter’s Five Forces Analysis for Fatty bases for suppositories market:
- Bargaining Power of Suppliers: The distribution channel as well as raw material suppliers in this field are low. However, these suppliers are mainly focusing on product differentiation and quality.
Thus, the bargaining power of suppliers is MODERATE.
- Bargaining Power of Buyer: The switching cost, backward integration, and product dependence of the fat excipient are critically low.
Therefore, the bargaining power of the buyer is LOW.
- Threat of New Entrants: Government regulations along with lower product differentiation offer a moderate threat of entry from emerging competitors.
The threat of new entrants is MODERATE.
- Threat of Substitutes: The supportive government policies are low for the fatty bases for suppositories market. In addition, brand loyalty and product differentiation is quite low
Thus, the threat of substitutes is LOW.
- Competitive Rivalry in the Market: Fatty bases for suppositories market has a moderate number of large, small, and medium companies. Also, industry players are mainly concentrating on alternative effective strategies such as strategic partnerships, product innovations.
Therefore, the competitive rivalry in the industry is MODERATE.
Historical Market Estimations
Base Year for Market Estimation
Forecast timeline for Market Projection
North America, Europe, Asia-Pacific, LAMEA
Segmentation by Excipient Base Type
Key Countries Covered
U.S., Canada, Mexico, Germany, France, UK, Italy, Spain, Russia, Rest of Europe, China, Japan, India, Australia, South Korea, Rest of Asia-Pacific, Brazil, Saudi Arabia, United Arab Emirates, Rest of LAMEA
Key Companies Profiled
Q1. What is the size of the Fatty bases for suppositories Market?
A. The global Fatty bases for suppositories market size was over $5,246.5 million in 2019 and is projected to reach $6,565.1 million by 2027.
Q2. Which are the major companies in the Fatty bases for suppositories Market?
A. Unither, LGV, and Delpharm are some of the key players in the global Fatty bases for suppositories Market.
Q3. Which region possesses greater investment opportunities in the coming future?
A. The European region possesses great investment opportunities for investors to witness the most promising growth in the future.
Q4. What is the growth rate of the European market?
A. The European market fatty bases for suppositories Market is anticipated to grow at 3.2% CAGR during the forecast period.
Q5. What are the strategies opted by the leading players in this market?
A. Technological advancements, product development, along with joint ventures are the key strategies opted by the operating companies in this market.
Q6. Which companies are investing more on R&D practices?
A. ATRAL and Delpharm companies are investing more on R&D activities for developing new products and technologies.
CHAPTER 1: INTRODUCTION
1.1. Research methodology
1.1.1. Desk research
1.1.2. Real-time insights and validation
1.1.3. Forecast model
1.1.4. Assumptions & forecast parameters
18.104.22.168. Forecast parameters
CHAPTER 2: EXECUTIVE SUMMARY
2.1. 360° summary
2.2. Excipient base type trends
CHAPTER 3: MARKET OVERVIEW
3.1. Market segmentation & definitions
3.2. Key takeaways
3.2.1. Top investment pockets
3.3. Porter’s five forces analysis
3.4. Market dynamics
22.214.171.124. Superior procedural outcomes to drive the market growth
126.96.36.199. Aging population
188.8.131.52. Reluctance of patients to prefer rectal drug delivery
184.108.40.206. Antiretroviral suppository drugs to treat viral infections to create lucrative market opportunities
3.5. Regulatory landscape
3.6. Patent landscape
3.7. Market value chain analysis
3.8. Strategic overview
CHAPTER 4: IMPACT OF COVID19 ON GLOBAL FATTY BASES FOR SUPPOSITORIES MARKET
4.2. COVID-19 health assessment
4.3. Impact of COVID-19 on the global economy
4.4. Impact of COVID-19 on global fatty bases for suppositories market
4.4.1. Social impact
4.4.2. Technological impact
4.4.3. Investment scenario
4.5. Fatty bases for suppositories market size and forecast, by region, 2019-2021
CHAPTER 5: GLOBAL FATTY BASES FOR SUPPOSITORIES MARKET, BY EXCIPIENT BASE TYPE
5.1.1. Market size and forecast, by excipient base type
5.2. Hard fat
5.2.1. Market size and forecast, by region
5.2.2. Market share analysis, by country
5.3. Macrogol (PEG)
5.3.1. Market size and forecast, by region
5.3.2. Market share analysis, by country
5.4. Glycerol + water
5.4.1. Market size and forecast, by region
5.4.2. Market share analysis, by country
5.5.1. Market size and forecast, by region
5.5.2. Market share analysis, by country
5.6. Cocoa butter
5.6.1. Market size and forecast, by region
5.6.2. Market share analysis, by country
CHAPTER 6: GLOBAL FATTY BASES FOR SUPPOSITORIES MARKET, BY REGION
6.1.1. Market size and forecast, by region
6.2. North America
6.2.1. Key market trends, growth factors, and opportunities
6.2.2. Market size and forecast, by excipient base type
6.2.3. Market size and forecast, by country
220.127.116.11. Market size and forecast, by excipient base type
18.104.22.168. Market size and forecast, by excipient base type
22.214.171.124. Market size and forecast, by excipient base type
6.3.1. Key market trends, growth factors, and opportunities
6.3.2. Market size and forecast, by excipient base type
6.3.3. Market size and forecast, by country
126.96.36.199. Market size and forecast, by excipient base type
188.8.131.52. Market size and forecast, by excipient base type
184.108.40.206. Market size and forecast, by excipient base type
220.127.116.11. Market size and forecast, by excipient base type
18.104.22.168. Market size and forecast, by excipient base type
6.3.9. Rest of Europe
22.214.171.124. Market size and forecast, by excipient base type
6.4.1. Key market trends, growth factors, and opportunities
6.4.2. Market size and forecast, by excipient base type
6.4.3. Market size and forecast, by country
126.96.36.199. Market size and forecast, by excipient base type
188.8.131.52. Market size and forecast, by excipient base type
184.108.40.206. Market size and forecast, by excipient base type
6.4.7. South Korea
220.127.116.11. Market size and forecast, by excipient base type
18.104.22.168. Market size and forecast, by excipient base type
6.4.9. Rest of Asia-Pacific
22.214.171.124. Market size and forecast, by excipient base type
6.5.1. Key market trends, growth factors, and opportunities
6.5.2. Market size and forecast, by excipient base type
6.5.3. Market size and forecast, by country
6.5.4. Latin America
126.96.36.199. Market size and forecast, by excipient base type
6.5.5. Middle East
188.8.131.52. Market size and forecast, by excipient base type
184.108.40.206. Market size and forecast, by excipient base type
CHAPTER 7: COMPANY PROFILES
7.1.1. Company overview
7.1.2. Company snapshot
7.1.3. Operating business segments
7.1.4. Business performance
7.2. Bliss GVS Pharma Ltd.
7.2.1. Company overview
7.2.2. Company snapshot
7.2.3. Operating business segments
7.2.4. Product portfolio
7.2.5. Business performance
7.3.1. Company overview
7.3.2. Company snapshot
7.3.3. Product portfolio
7.3.4. Key strategy moves and development
7.4.1. Company overview
7.4.2. Company snapshot
7.5. Aenova Holding GmbH
7.5.1. Company overview
7.5.2. Company snapshot
7.5.3. Operating business segments
7.5.4. Product portfolio
7.6.1. Company overview
7.6.2. Company snapshot
7.6.3. Operating business segments
7.6.4. Product portfolio
7.7. LGV (Laboratories Mayoly Spindler)
7.7.1. Company overview
7.7.2. Company snapshot
7.7.3. Operating business segments
7.7.4. Product portfolio
7.8. Priyans Drugs
7.8.1. Company overview
7.8.2. Company snapshot
7.8.3. Product portfolio
The present-day healthcare industry is seeking better replacements and improved medications that can substantially help patients to get better and be assured of having the least complications after being treated for infectious diseases. Perpetual research and development is being carried out all over the world by numerous institutes, research labs, and organizations in the field of fatty bases for suppository drug delivery medication.
Suppositories are a type of dosage designed to deliver medications via rectal and vaginal routes of administration. They have evolved as a more convenient alternative form of drug delivery from liquid enema formulations. Long back, during World War II due to dearth in cocoa butter, fatty bases (triglycerides) were introduced as suppository bases. Cocoa butter also called theobroma oil, is significantly used as a suppository base in numerous medicinal preparations.
Why is the Demand for Fatty Bases for Suppositories on Rise?
The incredible benefits of fat-based suppositories such as prompt absorption of numerous low molecular weight drugs, retaining of huge volumes, the potential for absorption into the lymphatic system, and the possibility of rate-controlled drug delivery are chiefly responsible to hasten the demand for fat-based suppositories.
Furthermore, massively increased implementation of fatty bases for suppositories for the rectal drug administration is fueling the demand for fat-based suppositories. In addition, fatty bases are extensively suggested as suppositories as they have a melting point of 37°C, which is equal to human body temperature, hence, this property helps in subsequent absorption and facilitates drug delivery.
In the present day, the rising elderly population is greatly susceptible to chronic disorders like cardiovascular diseases, orthopedic disorders, diabetes, and many more. An upsurge in the occurrence of such health disorders is rising the necessity to invent and manufacture advanced drugs. All these factors are a clear indication that the demand for fatty bases for suppositories is likely to propel in the global market in the near future.
What is Trending in the Fatty Bases for Suppositories Industry?
In the past few years, the world has observed significant developments in the healthcare sector. One of such inventions is the development of novel drug delivery systems like vaginal and rectal disintegrating tablet delivery systems that offer constant, accurate, timely, and more targeted absorption, mainly in aged patients. As per researchers, the rectal route can be well-thought-out as a better substitute to the oral route for elderly patients; particularly due to dysphagia.
Moreover, as per a survey, several patients of gynecological and urology disorders have been observed in the North American region. Hence, researchers have predicted that the demand for the medications especially for fat suppositories will be on rise in this region and is expected to remain in-demand in the future. According to the publication of CDC, in the U. S., bacterial vaginosis (BV) is one of the most common bacterial infections and about 30% of women in their reproductive phase are victims of this disease; fat-based suppositories has the potential to cure this infection. Furthermore, in line with clinical experiments carried out by scientists at the National Institute of Allergy and Infectious Diseases (NIAID), fat-based suppositories hold enormous importance in the hindrance of vaginal infections. These suppositories are extremely effective on infections including trichomoniasis, yeast infections, and bacterial vaginosis.
The fatty bases for suppositories sector has witnessed many product launches in the last few years. For instance, in July 2017, Cipla, a leading multinational pharmaceutical company has launched oil-based rectal suppositories to treat pediatric patients suffering from malaria. The company is focusing on providing rectal artesunate suppositories to rural areas of Africa to cure malaria. Overall the industry has perceived significant growth in the previous years, however, the outbreak of COVID-19 has created a negative impact on the growth of the fatty bases for suppositories market; the prime reason behind this stunted growth is the enforcement of huge pressure on the healthcare sector to invent vaccine and drugs against COVID-19 disease. The COVID-19 disaster has ultimately shifted the focus of pharmaceutical companies from their regular manufacturing of fat-based suppositories.
Future Scope of Fatty Bases for Suppositories Industry
As per a research report by Research Dive, the global fatty bases for suppositories market is expected to observe augmented growth and garner $6,565.1 million by 2027. Regardless of an extensive history of usage of vaginal and rectal drug delivery, the present-day global suppositories market is restricted mainly owing to a lack of acceptance for this drug delivery system by patients. For that reason, nearly no lucid pharmaceutical invention of antiviral suppositories has been accomplished. But, suppositories provide numerous benefits over other antiviral dosage methods. Modern suppository designs have combined active pharmaceutical components into prevailing formulation designs without optimization. Intrinsically, evolving suppository developments are targeted toward enhancing the current traditional design to improve drug delivery and is expected to expose suppository drug delivery systems to an extensive range of drugs, including antiretroviral products.