The present-day healthcare industry is seeking better replacements and improved medications that can substantially help patients to get better and be assured of having the least complications after being treated for infectious diseases. Perpetual research and development is being carried out all over the world by numerous institutes, research labs, and organizations in the field of fatty bases for suppository drug delivery medication.
Suppositories are a type of dosage designed to deliver medications via rectal and vaginal routes of administration. They have evolved as a more convenient alternative form of drug delivery from liquid enema formulations. Long back, during World War II due to dearth in cocoa butter, fatty bases (triglycerides) were introduced as suppository bases. Cocoa butter also called theobroma oil, is significantly used as a suppository base in numerous medicinal preparations.
Why is the Demand for Fatty Bases for Suppositories on Rise?
The incredible benefits of fat-based suppositories such as prompt absorption of numerous low molecular weight drugs, retaining of huge volumes, the potential for absorption into the lymphatic system, and the possibility of rate-controlled drug delivery are chiefly responsible to hasten the demand for fat-based suppositories.
Furthermore, massively increased implementation of fatty bases for suppositories for the rectal drug administration is fueling the demand for fat-based suppositories. In addition, fatty bases are extensively suggested as suppositories as they have a melting point of 37°C, which is equal to human body temperature, hence, this property helps in subsequent absorption and facilitates drug delivery.
In the present day, the rising elderly population is greatly susceptible to chronic disorders like cardiovascular diseases, orthopedic disorders, diabetes, and many more. An upsurge in the occurrence of such health disorders is rising the necessity to invent and manufacture advanced drugs. All these factors are a clear indication that the demand for fatty bases for suppositories is likely to propel in the global market in the near future.
What is Trending in the Fatty Bases for Suppositories Industry?
In the past few years, the world has observed significant developments in the healthcare sector. One of such inventions is the development of novel drug delivery systems like vaginal and rectal disintegrating tablet delivery systems that offer constant, accurate, timely, and more targeted absorption, mainly in aged patients. As per researchers, the rectal route can be well-thought-out as a better substitute to the oral route for elderly patients; particularly due to dysphagia.
Moreover, as per a survey, several patients of gynecological and urology disorders have been observed in the North American region. Hence, researchers have predicted that the demand for the medications especially for fat suppositories will be on rise in this region and is expected to remain in-demand in the future. According to the publication of CDC, in the U. S., bacterial vaginosis (BV) is one of the most common bacterial infections and about 30% of women in their reproductive phase are victims of this disease; fat-based suppositories has the potential to cure this infection. Furthermore, in line with clinical experiments carried out by scientists at the National Institute of Allergy and Infectious Diseases (NIAID), fat-based suppositories hold enormous importance in the hindrance of vaginal infections. These suppositories are extremely effective on infections including trichomoniasis, yeast infections, and bacterial vaginosis.
The fatty bases for suppositories sector has witnessed many product launches in the last few years. For instance, in July 2017, Cipla, a leading multinational pharmaceutical company has launched oil-based rectal suppositories to treat pediatric patients suffering from malaria. The company is focusing on providing rectal artesunate suppositories to rural areas of Africa to cure malaria. Overall the industry has perceived significant growth in the previous years, however, the outbreak of COVID-19 has created a negative impact on the growth of the fatty bases for suppositories market; the prime reason behind this stunted growth is the enforcement of huge pressure on the healthcare sector to invent vaccine and drugs against COVID-19 disease. The COVID-19 disaster has ultimately shifted the focus of pharmaceutical companies from their regular manufacturing of fat-based suppositories.
Future Scope of Fatty Bases for Suppositories Industry
As per a research report by Research Dive, the global fatty bases for suppositories market is expected to observe augmented growth and garner $6,565.1 million by 2027. Regardless of an extensive history of usage of vaginal and rectal drug delivery, the present-day global suppositories market is restricted mainly owing to a lack of acceptance for this drug delivery system by patients. For that reason, nearly no lucid pharmaceutical invention of antiviral suppositories has been accomplished. But, suppositories provide numerous benefits over other antiviral dosage methods. Modern suppository designs have combined active pharmaceutical components into prevailing formulation designs without optimization. Intrinsically, evolving suppository developments are targeted toward enhancing the current traditional design to improve drug delivery and is expected to expose suppository drug delivery systems to an extensive range of drugs, including antiretroviral products.