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Gene Synthesis Market Report

RA08565

Gene Synthesis Market by Method (Solid Phase Synthesis, PCR Based Enzyme Synthesis, and CHIP Based DNA Synthesis), End-user (Academic & Research Institutes, Biotech & Pharmaceutical Companies, Diagnostic Laboratories, and Other), and Regional Analysis (North America, Europe, Asia-Pacific, and LAMEA): Global Opportunity Analysis and Industry Forecast, 2021–2028)

RA08565

Pages: 181

Feb 2022

COVID-19

pandemic has shown to have an enormous impact on most
industries.

Click Here to access our comprehensive analysis of the

Impact of covid-19 on Gene Synthesis Market

Global Gene Synthesis Market Analysis

The global gene synthesis market size is predicted to garner $42,14,890.1 thousand in the 20212028 timeframe, growing from $11,10,000.0 thousand in 2020, at a healthy CAGR of 18.5%.

Market Synopsis

Strategic alliances among market players, along with growing demands for gene synthesis in clinical testing across the globe, are expected to accelerate the growth of the gene synthesis market.

However, high cost of gene synthesis and lack of skilled professionals in the market are some of the growth-restricting factors for the market.

According to the regional analysis, the Asia-Pacific gene synthesis market size is anticipated to grow during the review period and generate a revenue of $9,14,631.1 thousand, with CAGR of 19.0% due to increasing research activities in the region.  

Gene Synthesis Overview

Gene Synthesis is the method of biology that is used to synthesize artificial genes in a laboratory setting. This type of method enables modification and creation of genetic sequences that offers enormous opportunities in biological functionality. Also, artificial gene synthesis doesn’t require template DNA, allowing DNA sequence to be synthesized in the laboratory. It has two main steps such as production of oligonucleotide fragments and connecting such oligonucleotide fragments via DNA assembly methods.

Covid-19 Impact on Gene Synthesis Market Shares

The novel coronavirus pandemic severely affected several industries. The global gene synthesis market experienced a notable positive growth during this period. The high growth of market is owing to use of gene synthesis in scientific research, thereby contributing towards the revenue growth. For instance, in 2020, National Institute of Standards and Technology (NIST), revealed that they have produced artificial gene fragments from the COVID-19 virus throughout the pandemic. Such above-stated factors showcase that the pandemic may have affected the market in positive way, and it will ultimately bring sustainable opportunities for gene synthesis market in the coming years.

Increasing Prevalence of Genetic Synthesis in Healthcare to Surge the Market Growth

The global gene synthesis industry is witnessing a massive growth mainly due to rising application of gene synthesis in healthcare. Furthermore, in recombinant DNA technology, gene synthesis is most widely accepted tool that includes recombinant protein production. For example, in July 2018, a UK agency named Innovate UK, revealed that they have funded approximately US$ 1.76 million in project for the development of a new approach for DNA synthesis. All such factors may fuel the growth of the global gene synthesis market.

Furthermore, gene synthesis industry players are adopting innovating strategies to attract customers. For instance, Novogene, largest provider of genomic services and solutions, offers wide range of gene synthesis services and products. These types of factors are predicted to drive the growth of the market.

To know more about global gene synthesis market trends, drivers, get in touch with our analysts here.

Lack of Skilled Professionals to Restrain the Market Growth

The lack of availability of professionals in the market is one of the major restraining factors for global gene synthesis market. Also, misuse of gene synthesis in terms of using gene information for various purposes other than forensic is another factor anticipated to hinder the market value of the gene synthesis in the next few years.

Growing Population with Genetic and Chronic Disorders to Create Massive Investment Opportunities

The global gene synthesis market is spreading at a very fast pace due to increasing demand for gene synthesis among the population with genetic and chronic disorders across the globe. Moreover, according to a research article by Science Direct in 2018, chronic diseases are one of the major problems in developed countries and 80% of deaths in middle-low income countries are caused due to chronic diseases such as cancer in aging population. The increasing demand for targeted and personalized medicine among the population are some of the elements that will rise the gene synthesis market positively.

Furthermore, rising investment in the synthetic biology by government and private & public companies is expected to accelerate the overall gene synthesis market and bring lucrative market opportunities for key players in the upcoming years.

To know more about global gene synthesis market trends, opportunities, get in touch with our analysts here.

Gene Synthesis Market
By Method

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Based on method, the market has been divided into Solid Phase Synthesis, PCR based enzyme synthesis, and CHIP based DNA synthesis sub-segments of which the solid phase synthesis sub-segment is projected to generate the maximum revenue as well as show the fastest growth. Download PDF Sample Report

Source: Research Dive Analysis

The solid phase synthesis sub-segment is predicted to have a dominating share as well as fastest market growth in the global market and register a revenue of $20,06,287.7 thousand during the forecast period. Solid-phase synthesis method is more efficient, faster, and economical as compared to other gene synthesis method; thereby driving the global gene synthesis market. Furthermore, compatibility of solid-phase synthesis method in automated synthesis technology may bolster the growth of the sub-segment during the forecast period and gene synthesis market demand.

Gene Synthesis Market
By End User

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On the basis of end-user, the market has been sub-segmented into Academic & Research Institutes, biotech & pharmaceutical companies, diagnostic laboratories, and other sub-segments. Among the mentioned sub-segments, the academic & research sub-segment is predicted to show the dominant market share and experience fastest growth.

Source: Research Dive Analysis

The academic & research sub-segment is predicted to have a leading market share and fastest growth in gene synthesis globally and register a revenue of $17,36,534.7 thousand during the analysis timeframe owing to high use of gene synthesis in academic & research. High growth of the sub-segment is owing to government support and funding along with partnerships among the various organizations across the regions. Such factors may create huge opportunities for the sub-segment throughout the forecast period.

Gene Synthesis Market
By Region

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The gene synthesis market share was investigated across North America, Europe, Asia-Pacific, and LAMEA.

Source: Research Dive Analysis

The Market for Gene Synthesis in North America to be the Most Dominant

The North America gene synthesis market accounted $4,28,460.0 thousand in 2020 and is projected to register a revenue of $16,31,162.5 thousand by 2028. The extensive growth of the North America gene synthesis market is mainly driven by factors such as increasing research activities in the field of gene synthesis and more. Also, in North American countries, the existence of top leading companies is augmenting the industry growth in the region. These are some of the factors that are fueling the market growth across the globe.  

The Market for Gene Synthesis in Asia-Pacific to be the Fastest Growing

The share of Asia-Pacific gene synthesis market is expected to rise at a CAGR of 19.0%, by registering a revenue of $9,14,631.1 thousand by 2028. The growth shall be a result of rising demand for gene synthesis across the region owing to increasing population with genetic defects and chronic diseases. Furthermore, prevalence of R&D in the region helps to build genes, operons, and variant libraries to test the particular gene, which is expected to boost the demand for gene synthesis market.

Competitive Scenario in the Global Gene Synthesis Market

Product launches and mergers & acquisitions are common strategies followed by major market players.

Competitive Scenario in the Global Gene Synthesis Market

Source: Research Dive Analysis

Some of the leading gene synthesis market players are GenScript, Brooks Automation, Inc. (GENEWIZ), Boster Biological Technology, Twist Bioscience, Codex DNA, Biomatik, ProMab Biotechnologies, Inc., Thermo Fisher Scientific, Inc., Integrated DNA Technologies, Inc. and OriGene Technologies, Inc.

Porter’s Five Forces Analysis for the Global Gene Synthesis Market:

  • Bargaining Power of Suppliers: The product suppliers of gene synthesis market are high in number and are larger and more globalized. Bargaining power of suppliers depends upon production process and type of gene synthesis.
    Thus, the bargaining power of suppliers is low. 
  • Bargaining Power of Buyers: Buyers have huge options to select from more than top companies of gene synthesis; this has increased the pressure on the gene synthesis providers to offer the best services to the consumer. This gives the buyers the option to freely choose gene synthesis products and services that best fit their preference.
    Thus, the bargaining power of the buyers is high. 
  • Threat of New Entrants: Companies entering the gene synthesis market are adopting various innovations.
    Thus, the threat of the new entrants is high.
  • Threat of Substitutes: Different types of synthetic biology methods and technologies are present, but gene synthesis is considered as the best method to synthesize gene artificially.
    Thus, the threat of substitutes is low.
  • Competitive Rivalry in the Market: The competitive rivalry among industry leaders is rather intense, especially between the global players including GenScript and Thermo Fisher Scientific, Inc. These companies are launching their value-added services in the international market and strengthening the footprint worldwide.
    Therefore, competitive rivalry in the market is high.

Aspect

Particulars

  Historical Market Estimations

  2019-2020

  Base Year for Market Estimation

  2020

  Forecast Timeline for Market Projection

  2021-2028

  Geographical Scope

  North America, Europe, Asia-Pacific, LAMEA

  Segmentation by Method

  • Solid Phase Synthesis
  • PCR Based Enzyme Synthesis
  • CHIP Based DNA Synthesis

  Segmentation by End-user

  • Academic & Research Institutes
  • Biotech & Pharmaceutical Companies
  • Diagnostic Laboratories,
  • Other

  Key Companies Profiled

  • GenScript
  • Brooks Automation, Inc. (GENEWIZ)
  • Boster Biological Technology
  • Twist Bioscience
  • Codex DNA
  • Biomatik
  • ProMab Biotechnologies, Inc.
  • Thermo Fisher Scientific, Inc.
  • Integrated DNA Technologies, Inc.
  • OriGene Technologies, Inc.

Frequently Asked Questions
 

A. The size of the global gene synthesis market was over $11,10,000.0 thousand in 2020 and is projected to reach $42,14,890.1 thousand by 2028.

A. GenScript and Thermo Fisher Scientific, Inc. are some of the key players in the global gene synthesis market.

A. The Asia-Pacific region possesses great investment opportunities for investors to witness the most promising growth in the future.

A. Asia-Pacific gene synthesis market is anticipated to grow at 19.0% CAGR during the forecast period.

A. Technological development and strategic partnerships are the key strategies opted by the operating companies in this market.

1.Research Methodology

1.1.Desk Research
1.2.Real time insights and validation
1.3.Forecast model
1.4.Assumptions and forecast parameters

1.4.1.Assumptions
1.4.2.Forecast parameters

1.5.Data sources

1.5.1.Primary
1.5.2.Secondary

2.Executive Summary

2.1.360° summary
2.2.By Method trends
2.3.By End User trends 

3.Market overview

3.1.Market segmentation & definitions
3.2.Key takeaways

3.2.1.Top investment pockets
3.2.2.Top winning strategies

3.3.Porter’s five forces analysis

3.3.1.Bargaining power of consumers
3.3.2.Bargaining power of suppliers
3.3.3.Threat of new entrants
3.3.4.Threat of substitutes
3.3.5.Competitive rivalry in the market

3.4.Market dynamics

3.4.1.Drivers
3.4.2.Restraints
3.4.3.Opportunities

3.5.Technology landscape
3.6.Regulatory landscape
3.7.Patent landscape
3.8.Market value chain analysis

3.8.1.Stress point analysis
3.8.2.Raw material analysis
3.8.3.Manufacturing process
3.8.4.Sales Channel analysis
3.8.5.Operating vendors

3.8.5.1.Raw material suppliers
3.8.5.2.type manufacturers
3.8.5.3.type distributors

3.9.Strategic overview

4.Gene Synthesis Market, by Method

4.1.Overview

4.1.1.Market size and forecast, by type

4.2.Solid Phase Synthesis

4.2.1.Key market trends, growth factors, and opportunities
4.2.2.Market size and forecast, by region, 2020-2028
4.2.3.Market share analysis, by country 2020 & 2028

4.3.PCR Based Enzyme Synthesis

4.3.1.Key market trends, growth factors, and opportunities
4.3.2.Market size and forecast, by region, 2020-2028
4.3.3.Market share analysis, by country 2020 & 2028

4.4.CHIP Based DNA Synthesis

4.4.1.Key market trends, growth factors, and opportunities
4.4.2.Market size and forecast, by region, 2020-2028
4.4.3.Market share analysis, by country 2020 & 2028

5.Gene Synthesis Market, by End-User

5.1.Overview

5.1.1.Market size and forecast, by Sales Channel

5.2. Academic & Research Institutes,

5.2.1.Key market trends, growth factors, and opportunities
5.2.2.Market size and forecast, by region, 2020-2028
5.2.3.Market share analysis, by country 2020 & 2028

5.3.Biotech & Pharmaceutical Companies,

5.3.1.Key market trends, growth factors, and opportunities
5.3.2.Market size and forecast, by region, 2020-2028
5.3.3.Market share analysis, by country 2020 & 2028 

5.4.Diagnostic Laboratories,

5.4.1.Key market trends, growth factors, and opportunities
5.4.2.Market size and forecast, by region, 2020-2028
5.4.3.Market share analysis, by country 2020 & 2028

5.5.Others

5.5.1.Key market trends, growth factors, and opportunities
5.5.2.Market size and forecast, by region, 2020-2028
5.5.3.Market share analysis, by country 2020 & 2028 

6.Gene Synthesis Market, by Region

6.1.Overview

6.1.1.Market size and forecast, by region

6.2.North America

6.2.1.Key market trends, growth factors, and opportunities
6.2.2.Market size and forecast, by Method, 2020-2028
6.2.3.Market size and forecast, by End-User, 2020-2028
6.2.4.Market size and forecast, by country, 2020-2028

6.2.5.U.S.

6.2.5.1.Market size and forecast, by Method, 2020-2028
6.2.6.Market size and forecast, by End-User, 2020-2028

6.2.7.Canada

6.2.7.1.Market size and forecast, by Method, 2020-2028
6.2.8.Market size and forecast, by End-User, 2020-2028

6.2.9.Mexico
6.2.10.Market size and forecast, by End-User, 2020-2028

6.3.Europe

6.3.1.Key market trends, growth factors, and opportunities
6.3.2.Market size and forecast, by Method, 2020-2028
6.3.3.Market size and forecast, by End-User, 2020-2028
6.3.4.Market size and forecast, by country, 2020-2028

6.3.5.Germany 

6.3.5.1.Market size and forecast, by Method, 2020-2028
6.3.6.Market size and forecast, by End-User, 2020-2028

6.3.7.UK

6.3.7.1.Market size and forecast, by Method, 2020-2028
6.3.7.2.Market size and forecast, by End-User, 2020-2028

6.3.8.France

6.3.8.1.Market size and forecast, by Method, 2020-2028
6.3.8.2.Market size and forecast, by End-User, 2020-2028

6.3.9.Spain

6.3.9.1.Market size and forecast, by Method, 2020-2028
6.3.9.2.Market size and forecast, by End-User, 2020-2028

6.3.10.Italy 

6.3.10.1.Market size and forecast, by Method, 2020-2028
6.3.10.2.Market size and forecast, by End-User, 2020-2028

6.3.11.Rest of Europe

6.3.11.1.Market size and forecast, by Method, 2020-2028
6.3.11.2.Market size and forecast, by End-User, 2020-2028

6.4.Asia Pacific

6.4.1.Key market trends, growth factors, and opportunities
6.4.2.Market size and forecast, by Method, 2020-2028
6.4.3.Market size and forecast, by End-User, 2020-2028
6.4.4.Market size and forecast, by country, 2020-2028

6.4.5.China

6.4.5.1.Market size and forecast, by Method, 2020-2028
6.4.5.2.Market size and forecast, by End-User, 2020-2028

6.4.6.Japan

6.4.6.1.Market size and forecast, by Method, 2020-2028
6.4.6.2.Market size and forecast, by End-User, 2020-2028

6.4.7.India 

6.4.7.1.Market size and forecast, by Method, 2020-2028
6.4.7.2.Market size and forecast, by End-User, 2020-2028

6.4.8.South Korea

6.4.8.1.Market size and forecast, by Method, 2020-2028
6.4.8.2.Market size and forecast, by End-User, 2020-2028

6.4.9.Australia 

6.4.9.1.Market size and forecast, by Method, 2020 2028
6.4.9.2.Market size and forecast, by End-User, 2020-2028
6.4.9.3.Comparative market share analysis, 2020 & 2028

6.4.10.Rest of Asia Pacific

6.4.10.1.Market size and forecast, by Method, 2020-2028
6.4.10.2.Market size and forecast, by End-User, 2020-2028

6.5.LAMEA

6.5.1.Key market trends, growth factors, and opportunities
6.5.2.Market size and forecast, by Method, 2020-2028
6.5.2.1.Market size and forecast, by End-User, 2020-2028
6.5.3.Market size and forecast, by country, 2020-2028

6.5.4.Latin America  

6.5.4.1.Market size and forecast, by Method, 2020-2028
6.5.4.2.Market size and forecast, by End-User, 2020-2028

6.5.5.Middle East 

6.5.5.1.Market size and forecast, by Method, 2020-2028
6.5.5.2.Market size and forecast, by End-User, 2020-2028

6.5.6.Africa

6.5.6.1.Market size and forecast, by Method, 2020-2028
6.5.6.2.Market size and forecast, by End-User, 2020-2028

7.Company profiles

7.1.GenScript 

7.1.1.Company overview
7.1.2.Operating business segments
7.1.3.Method portfolio
7.1.4.Financial Performance
7.1.5.Recent strategic moves & developments

7.2.Brooks Automation, Inc

7.2.1.Company overview
7.2.2.Operating business segments
7.2.3.Method portfolio
7.2.4.Financial Performance
7.2.5.Recent strategic moves & developments

7.3.Boster Biological Technology

7.3.1.Company overview
7.3.2.Operating business segments
7.3.3.Method portfolio
7.3.4.Financial Performance
7.3.5.Recent strategic moves & developments

7.4.Twist Bioscience

7.4.1.Company overview
7.4.2.Operating business segments
7.4.3.Method portfolio
7.4.4.Financial Performance
7.4.5.Recent strategic moves & developments

7.5.ProteoGenix

7.5.1.Company overview
7.5.2.Operating business segments
7.5.3.Method portfolio
7.5.4.Financial Performance
7.5.5.Recent strategic moves & developments

7.6.Biomatik,

7.6.1.Company overview
7.6.2.Operating business segments
7.6.3.Method portfolio
7.6.4.Financial Performance
7.6.5.Recent strategic moves & developments

7.7.ProMab Biotechnologies, Inc.

7.7.1.Company overview
7.7.2.Operating business segments
7.7.3.Method portfolio
7.7.4.Financial Performance
7.7.5.Recent strategic moves & developments

7.8.Thermo Fisher Scientific, Inc.

7.8.1.Company overview
7.8.2.Operating business segments
7.8.3.Method portfolio
7.8.4.Financial Performance
7.8.5.Recent strategic moves & developments

7.9.Integrated DNA Technologies, Inc.

7.9.1.Company overview
7.9.2.Operating business segments
7.9.3.Method portfolio
7.9.4.Financial Performance
7.9.5.Recent strategic moves & developments

7.10.OriGene Technologies, Inc. 

7.10.1.Company overview
7.10.2.Operating business segments
7.10.3.Method portfolio
7.10.4.Financial Performance
7.10.5.Recent strategic moves & developments

Gene synthesis is swiftly revolutionizing biomedical research. Gene synthesis services are significantly turning out to be a key part of current biological research processes. Gene synthesis, which is also called DNA synthesis, is the formation of gene-length double-stranded DNA fragments.

This technique is not new. The first gene was synthesized in 1970 as a part of an effort to decrypt a genetic code. Nevertheless, this technology has been accessible as a service from the year 2000. Today, gene synthesis is used to produce plasmids designed in computers, enhance gene expression, and in several other application areas.

Since then, an uncountable number of gene synthesis companies have developed. The global gene synthesis market is perceiving enormous growth mostly owing to the mounting applications of gene synthesis in the healthcare sector. Additionally, in recombinant DNA technology, gene synthesis is extensively accepted tool that comprises recombinant protein production. Moreover, the rising demand for gene synthesis amongst the population with genetic and chronic disorders across the globe and rising investments in the synthetic biology by government organizations and private & public companies are predicted to hasten the global gene synthesis market growth. This is going to pave way for lucrative opportunities for the leading companies functioning in the market in the forthcoming years.

Latest Trends in the Gene Synthesis Market

As per a report by Research Dive, the global gene synthesis market is expected to grow from $11,10,000.0 thousand in 2020 to $42,14,890.1 thousand by 2028. The North America region is the leading user of gene synthesis technique and is expected to take over the major share of the gene synthesis market by garnering a revenue of $16,31,162.5 thousand by 2028.

Moreover, the gene synthesis market in Asia-Pacific is anticipated to grow rapidly with a CAGR of 19.0% from 2021 to 2028. This is mainly owing to the growing rising demand for gene synthesis in this region due to presence of huge population with genetic defects and chronic ailments. Market players are considerably investing in research and development to cater the mounting demand for gene synthesis in research activities. Some of the leading players of the gene synthesis market are Brooks Automation, Inc. (GENEWIZ), Twist Bioscience, Codex DNA, Biomatik, ProMab Biotechnologies, Inc., Boster Biological Technology, Integrated DNA Technologies, Inc., GenScript, OriGene Technologies, Inc., Thermo Fisher Scientific, Inc., and others. These players are concentrated on developing strategies such as mergers and acquisitions, partnerships, novel developments, and collaborations to achieve a prominent position in the global market.

For instance,

  • In June 2019, GenScript®, the global leader in offering gene synthesis services, introduced a substantial upgrade to its GenBrick™ Gene Synthesis platform, bringing scientists access to DNA sequences up to 200kb long with 100% precision.
     
  • In November 2021, OriCiro Genomics, a forerunner in cell-free synthesis and strengthening of genome-scale large DNA for advanced therapeutics and synthetic biology, launched an innovative enzymatic DNA synthesis tool for frequently used vectors.
     
  • In November 2021, Codex DNA, Inc., a synthetic biology company focused on the development of automation solutions for DNA, RNA, and protein synthesis, announced the commercial availability of automated mRNA synthesis kit with integrated capping technology for BioXp™ system.

COVID-19 Impact on the Gene Synthesis Market

The abrupt rise of the coronavirus pandemic in 2020 has positively impacted the global gene synthesis market. This is mainly due to the rising usage of gene synthesis in scientific research activities. For instance, in 2020, the National Institute of Standards and Technology (NIST), unveiled that they have formed artificial gene fragments from the COVID-19 virus. The use of gene synthesis in such developments is greatly contributing to the market growth. Moreover, as the worldwide economy is recovering with the relaxation of pandemic, the use of gene synthesis in medical research projects is gaining traction. This is likely to boom the gene synthesis market in the imminent years.

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